ZFIN is now using GRCz12tu for Genomic Data
Gene
pth1a
- ID
- ZDB-GENE-040623-1
- Name
- parathyroid hormone 1a
- Symbol
- pth1a Nomenclature History
- Previous Names
-
- pth1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables hormone activity. Acts upstream of or within calcium ion homeostasis and epidermal cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including gill; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism (multiple); hyperphosphatemia; and secondary hyperparathyroidism. Orthologous to human PTH (parathyroid hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial isolated hypoparathyroidism 1 | Alliance | Hypoparathyroidism, familial isolated 1 | 146200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Parathyroid hormone | Parathyroid hormone/parathyroid hormone-related protein |
|---|---|---|---|---|
| UniProtKB:Q6WQ25 | InterPro | 102 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers